Journal of International Medical Research, Volume 48, Issue 7, July 2020. PurposeTo investigate serum vitamin D levels in patients newly diagnosed with non-Hodgkin lymphoma/diffuse large B-cell lymphoma (NHL-DLBCL), multiple myeloma (MM) and chronic lymphocytic leukemia (CLL).Patients and methodsWe measured serum levels of vitamin D by ELISA in 103 patients prior to initiation of treatment, of whom 37 were diagnosed with MM, 32 with CLL and 34 with NHL-DLBCL.ResultsSuboptimal serum vitamin D levels...
Wed Jul 29, 2020 07:10
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveWe assessed the neuromechanical efficiency (NME), neuroventilatory efficiency (NVE), and diaphragmatic function effects between pressure support ventilation (PSV) and neutrally adjusted ventilatory assist (NAVA).MethodsFifteen patients who had undergone surgical treatment of intracerebral hemorrhage were enrolled in this randomized crossover study. The patients were assigned to PSV for the first 24 hours and then to...
Tue Jul 28, 2020 14:21
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveWe aimed to investigate the diagnostic value of microRNA-155 (miR-155) for acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) in patients with sepsis.MethodsIn this prospective study, we used Spearman correlation analysis to investigate relationships between miR-155 expression and inflammatory factors, oxygenation ratio (PaO2/FiO2), and ALI/ARDS score, and used area under the receiver operating characteristic...
Tue Jul 28, 2020 14:20
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo clarify differences in clinical characteristics and outcomes between patients with infective endocarditis (IE) receiving long-term haemodialysis (HD group) and those not receiving haemodialysis (non-HD group).MethodsMedical records of patients with IE, admitted to hospital between January 2010 and December 2017, were retrospectively studied. Clinical characteristics and outcomes were compared between HD and non-HD...
Tue Jul 28, 2020 14:20
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Myomectomy scar pregnancy (MSP) is a rare disease, which is defined as a gestational sac located within a previous myomectomy scar. MSP is an uncommon late complication of uterine fibroids after myomectomy. We report a case where the implantation site matched the site of the previous myomectomy, and review the existing literature. A 28-year-old pregnant woman presented with vaginal bleeding. She was diagnosed with MSP by ultrasound...
Tue Jul 28, 2020 13:44
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis study was performed to assess low-dose scan parameters in dual-energy computed tomography (CT) for displaying the anterior cruciate ligament.MethodsDual-energy CT scans with low and standard dose parameters, respectively, were performed in nine human knee joint specimens. Eighteen imaging data sets for cruciate ligament specimens were obtained and processed. Statistical analysis was performed for signal-to-noise...
Tue Jul 28, 2020 12:33
Journal of International Medical Research, Volume 48, Issue 7, July 2020. BackgroundThe underlying mechanism of micro (mi)RNA-211 in bone cell apoptosis after fracture remains unclear. This study aimed to determine the effect and function of miRNA-211 in bone cell apoptosis in fracture patients.MethodsSerum samples were collected from patients with fractures and healthy controls. Serum miR-211 expression was detected by quantitative PCR. MC3T3-E1 cells were transfected with a transforming growth...
Tue Jul 28, 2020 12:14
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveWith the development of human genomics, the genetic factors associated with dental caries have receiving increasing attention. This study was performed to evaluate the relationship between lactoferrin (LTF) and mannose-binding lectin 2 (MBL2) gene single nucleotide polymorphisms (SNPs) and dental caries susceptibility in Chinese children.MethodsThis prospective case–control study included 360 unrelated children (aged...
Tue Jul 28, 2020 10:08
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo investigate the anti-proliferative and pro-apoptotic effects of curcumin on diffuse large B-cell lymphoma (DLBCL) cells and explore the mechanism.MethodsOCI-LY7 cells were treated with curcumin (2.5, 5, 10, 20, and 40 μM) for 24, 48, or 72 hours. Cell viability and apoptosis were determined using the 3-(4, 5-dimethylthiazol-2-yl)-2, 5 diphenyl tetrazolium bromide assay and TdT-mediated dUTP nick-end labeling staining,...
Tue Jul 28, 2020 10:08
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis study was performed to evaluate the effect of care bundles on the prevention of central venous catheter-related bloodstream infection (CRBSI) and improvement of patients’ experience.MethodsIn total, 212 patients with central venous catheter insertions were enrolled in this study. All patients were matched by sex, age, Acute Physiology and Chronic Health Evaluation II score, body mass index, department, and catheter...
Tue Jul 28, 2020 04:24
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis study aimed to systematically assess the effect of the metastasis associated lung adenocarcinoma transcript 1 (MALAT1) long noncoding RNA rs619586 polymorphism on cancer risk.MethodsWe conducted a literature search of the PubMed, Embase, and China National Knowledge Internet databases to identify relevant studies, and calculated the pooled odds ratios (ORs) and 95% confidence intervals (CIs) for the retrieved...
Tue Jul 28, 2020 04:20
Journal of International Medical Research, Volume 48, Issue 7, July 2020. BackgroundStudies using 1 mg of colchicine to prevent postoperative atrial fibrillation (POAF) reported conflicting results. Moreover, colchicine was associated with significant gastrointestinal (GI) side effects. This study examined whether low-dose colchicine effectively prevents POAF and whether low-dose therapy is associated with lower rates of colchicine-induced GI side effects.MethodsIn this prospective, randomized, double-blind,...
Tue Jul 28, 2020 04:19
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveHepatocellular carcinoma (HCC) is one of the most common causes of cancer-related deaths worldwide. This study investigated the relationship between cyclin-dependent kinase inhibitor (CDKN)3 and prognosis and pathological characteristics in HCC patients to determine whether it could be used as a prognostic factor and/or therapeutic target for HCC drug development.MethodsWe previously showed that CDKN3 is deregulated...
Tue Jul 28, 2020 04:19
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